Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1804199 | Journal of Magnetism and Magnetic Materials | 2007 | 5 Pages |
Abstract
Analyses of food-borne pathogens are of great importance in order to minimize the health risk for customers. Thus, very sensitive and rapid detection methods are required. Current conventional culture techniques are very time consuming. Modern immunoassays and biochemical analysis also require pre-enrichment steps resulting in a turnaround time of at least 24 h. Biomagnetic separation (BMS) is a promising more rapid method. In this study we describe the isolation of high affine and specific peptides from a phage-peptide library, which combined with BMS allows the detection of Salmonella spp. with a similar sensitivity as that of immunomagnetic separation using antibodies.
Related Topics
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Authors
Juliane Steingroewer, Thomas Bley, Christian Bergemann, Elke Boschke,