Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1804203 | Journal of Magnetism and Magnetic Materials | 2007 | 5 Pages |
Abstract
Magnetic nanoparticles are good candidates used for the targeted delivery of anti-tumor agents. They can be concentrated on a desired region, reducing collateral effects and improving the efficiency of the chemotherapy. We propose a method in which permanent magnets are implanted by laparoscopic technique directly in the affected organ. This method proposes the use of Fe@C nanoparticles, which are loaded with doxorubicin and injected intravenously. The particles, once attracted to the magnet, release the drug at the tumor region. This method seems to be more promising and effective than that based on the application of external magnetic fields.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Condensed Matter Physics
Authors
Rodrigo Fernández-Pacheco, Clara Marquina, J. Gabriel Valdivia, Martín Gutiérrez, M. Soledad Romero, Rosa Cornudella, Alicia Laborda, Américo Viloria, Teresa Higuera, Alba García, J. Antonio García de Jalón, M. Ricardo Ibarra,