Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1804232 | Journal of Magnetism and Magnetic Materials | 2007 | 4 Pages |
Abstract
A magnetic AC susceptibility characterisation of rat tissues after intravenous administration of superparamagnetic iron oxide (Endorem®®), at the same dose as established for Magnetic Resonance Imaging (MRI) contrast enhancement in humans, has been carried out. The measurements reveal the presence of the contrast agent as well as that of physiological ferritin in liver and spleen while no traces have been magnetically detected in heart and kidney. This preliminary work opens suggestive possibilities for future biodistribution studies of any type of magnetic carriers.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Condensed Matter Physics
Authors
Francisco José Lázaro, Lucía Gutiérrez, Ana Rosa Abadía, María Soledad Romero, Antonio López, María Jesús Muñoz,