| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1814834 | Physica B: Condensed Matter | 2008 | 9 Pages |
The potential profile for a model of squid axon membrane has been determined for two physiological states: resting and action states. The non-linear Poisson–Boltzmann equation has been solved by considering the volumetric charge densities due to charges dissolved in an electrolytic solution and fixed on both glycocalyx and cytoplasmatic proteins. Results showing the features of the potential profile along the outer electrolytic region are similar for both resting and action states. However, the potential fall along glycocalyx at action state is lower than at resting. A small variation in the Na+ concentration drastically affects the surface membrane potentials and vice versa. We conclude that effects on the potential profile due to surface lipidic bilayer charge and contiguous electric double layers are more relevant than those provoked by fixed charges distributed along the cell cytoplasm.
