Article ID Journal Published Year Pages File Type
1859465 Physics Letters A 2016 6 Pages PDF
Abstract
We investigate intercellular insulin dynamics in an array of diffusively coupled pancreatic islet β-cells. The cells are connected via gap junction coupling, where nearest neighbor interactions are included. Through the multiple scale expansion in the semi-discrete approximation, we show that the insulin dynamics can be governed by the complex Ginzburg-Landau equation. The localized solutions of this equation are reported. The results suggest from the biophysical point of view that the insulin propagates in pancreatic islet β-cells using both temporal and spatial dimensions in the form of localized modulated waves.
Related Topics
Physical Sciences and Engineering Physics and Astronomy Physics and Astronomy (General)
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