| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1869119 | Physics Procedia | 2014 | 5 Pages |
Abstract
Blebs are membrane protrusions that appear during several physiological processes in eukaryotic cells. The phase behavior and kinetics of blebbing in cellular membrane is investigated computationally using a particle-based model for self-assembled lipid vesicles apposed to an elastic meshwork, mimicking a cell's cytoskeleton. We found that blebbing is induced when the cytoskeleton is subjected to a localized ablation, detachment from the membrane, or a uniform contraction. These results are in good agreement with experiments.
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