Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1875807 | Applied Radiation and Isotopes | 2015 | 9 Pages |
Abstract
In the same respect, the present work aims, for the first time to the authors' best knowledge, to explore whether TL can be employed as a method for post-sterilization dosimetry on commercial liquid-state drugs, by studying the properties of their glass containers. Two different types of glass containers (bottle and ampoule) of two widely used liquid drugs, i.e., Hexalen® and Voltaren®, are used for this purpose. Both glass containers exhibit a linear TL dose response for doses up to 6Â kGy with a stable behavior through time, while no significant sensitization of the main peaks is observed. Thus, preliminary findings are very promising towards the post-sterilization dosimetry of liquid drugs and the use of the containers of commercial liquid drugs for normal and/or accidental dosimetry.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Nikolaos A. Kazakis, Nestor C. Tsirliganis, George Kitis,