Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1876591 | Applied Radiation and Isotopes | 2010 | 9 Pages |
Abstract
60Cu and 64Cu are useful radioisotopes for positron emission tomography (PET) radiopharmaceuticals and may be used for the preparation of promising agents for diagnosis and radiotherapy. In this study, the production and purification of 60/64Cu starting from 60/64Ni using a new automated system, namely Alceo, is described. A dynamic process for electrodeposition and dissolution of 60/64Ni/60/64Cu was developed. Preliminary production yields of 60Cu and 64Cu were 400 and 300 mCi, respectively. 64Cu was used to radiolabel the hypoxia detection tracer ATSM with a specific activity of 2.2±1.3 Ci/μmol.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Mario Matarrese, Paolo Bedeschi, Roberto Scardaoni, Francesco Sudati, Annarita Savi, Annalisa Pepe, Valeria Masiello, Sergio Todde, Luigi Gianolli, Cristina Messa, Ferruccio Fazio,