Article ID Journal Published Year Pages File Type
1877178 Applied Radiation and Isotopes 2008 7 Pages PDF
Abstract

New [Ru(L1)(dcbpy)(NCS)2] complex was synthesized in a one-pot reaction starting from [RuCl2(p-cymene)]2, where the ligands (dcbpy=4,4′-dicarboxy-2,2′-bipyridine, L1=dipyrido[3,2-a:2′,3′-c]phenazine-11-ylcarbonyl)-sodium) are introduced sequentially. The resulting complex was characterized by IR, NMR, and elemental analysis. The complex was labeled with I-131. Biodistribution study of the complex was carried out using 131I-labeled [Ru(L1)(dcbpy)(NCS)2] complex. The biodistribution study performed with albino Wistar male rats has shown that the complex has high uptake in the lung, small intestine, fat, and spleen.

Related Topics
Physical Sciences and Engineering Physics and Astronomy Radiation
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