Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1877178 | Applied Radiation and Isotopes | 2008 | 7 Pages |
Abstract
New [Ru(L1)(dcbpy)(NCS)2] complex was synthesized in a one-pot reaction starting from [RuCl2(p-cymene)]2, where the ligands (dcbpy=4,4′-dicarboxy-2,2′-bipyridine, L1=dipyrido[3,2-a:2′,3′-c]phenazine-11-ylcarbonyl)-sodium) are introduced sequentially. The resulting complex was characterized by IR, NMR, and elemental analysis. The complex was labeled with I-131. Biodistribution study of the complex was carried out using 131I-labeled [Ru(L1)(dcbpy)(NCS)2] complex. The biodistribution study performed with albino Wistar male rats has shown that the complex has high uptake in the lung, small intestine, fat, and spleen.
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Radiation
Authors
Kasim Ocakoglu, Yeliz Yildirim, Fatma Yurt Lambrecht, Jale Ocal, Siddik Icli,