| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1877229 | Applied Radiation and Isotopes | 2007 | 6 Pages |
Abstract
The objective of this study was to verify that the [F-18]FDG PET synovial uptake is correlated with the synovial fluid (SF) TNF-α concentration. Two rabbit models of acute inflammatory arthritis induced by human interleukin-8 and lipopolysaccharide were used. Modified standard uptake values (MSUVs) obtained from PET images of the animals were compared with results of SF TNF-α measurements. Statistically significant correlations were found between the MSUVs and the SF TNF-α ratios. An equation to estimate the TNF-α ratio from a MSUV was also derived.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
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Authors
Po-Wei Lin, Ren-Shyan Liu, Tsan-Hon Liou, Li-Chern Pan, Chi-Hsien Chen,