Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1877363 | Applied Radiation and Isotopes | 2007 | 5 Pages |
Abstract
The widely used bifunctional labeling reagent 4-[18F]fluorobenzoic acid ([18F]FBA) and its activated form N-succinimidyl 4-[18F]fluorobenzoate ([18F]SFB) were prepared using a modified Siemens/CTI chemistry process control unit (CPCU) double vessel [18F]FDG module. The products were obtained with a radiochemical yield greater than 99% with decay corrected yields of 77±5% (n=4) for [18F]FBA and 46±5% (n=4) for [18F]SFB. The presented synthetic procedure is highly reproducible and fully automated.
Keywords
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Jan Marik, Julie L. Sutcliffe,