Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1877757 | Applied Radiation and Isotopes | 2011 | 5 Pages |
Abstract
The aim of these studies was to evaluate the mechanisms of cellular response to DNA damage induced by BNCT. Thyroid carcinoma cells were incubated with 10BPA or 10BOPP and irradiated with thermal neutrons. The surviving fraction, the cell cycle distribution and the expression of p53 and Ku70 were analyzed. Different cellular responses were observed for each irradiated group. The decrease of Ku70 in the neutrons +BOPP group could play a role in the increase of sensitization to radiation.
Keywords
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
M. Perona, O. Pontiggia, M. Carpano, L. Thomasz, S. Thorp, E. Pozzi, M. Simian, S. Kahl, G. Juvenal, M. Pisarev, A. Dagrosa,