| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1877915 | Applied Radiation and Isotopes | 2010 | 7 Pages |
Abstract
AimThe aim of this study was to evaluate early detection of temporomandibular joint (TMJ) inflammatory changes based on 1-thio-β-d-glucose radiolabeled with technetium-99m.MethodThe method applied a TMJ inflammation model in rats followed by radiopharmaceutical synthesis, intravenous administration of 99mTc-1-TG and kinetic scintigraphy imaging.ResultsResults show a significant difference of 99mTc-1-TG uptake between inflamed TMJ and the control joint. The biodistribution of 99mTc-1-TG by images showed the kidneys’ excretion.ConclusionAs conclusion, 99mTc-1-TG is a helpful tool in TMJ inflammatory process detection.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Cláudia Borges Brasileiro, Cinthia Mara da Fonseca Pacheco, Celso Martins Queiroz-Junior, Carla Flávia de Lima, Juliana Batista da Silva, Tarcísio Passos Ribeiro de Campos,