Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1878171 | Applied Radiation and Isotopes | 2009 | 7 Pages |
Abstract
In terms of the total uptake it was found that the compounds that were less lipophilic (MM5, MM6) were taken up less efficiently in cells than those that are more lipophilic. Therefore hydrophilic drugs are expected to have a limited biodistribution compared to lipophilic drugs. This might imply a more selective tumour uptake.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
M.J. Nell, J.M. Wagener, J.R. Zeevaart, E. Kilian, M.A. Mamo, M. Layh, M. Coyanis, C.E.J. van Rensburg,