Standardization of 18F and its use for the Romanian PET metrological traceability chain assurance

•Presents establishment of the 18F FDG Romanian PET traceability chain.•Shows work at IFIN-HH and at the users’ site.•An 18F solution was standardized by the 4πβ(PC)-γ coincidence method.•Includes measurement of half-life for detection of positron emitting impurities.•CENTRONIC IG12/20A ionization chamber and radionuclide calibrators calibrated.

This paper presents the work performed at IFIN-HH and at the users’ sites, aimed to establish the 18FDG Romanian PET traceability chain. It summarizes the operations: (i) Absolute standardization of a 18F solution, by the 4πβ(PC)-γ coincidence method; (ii) Control of gamma-ray impurity content and measurement of the activity by gamma ray spectrometry; (iii) Measurement of the half life, for detection of some short/long life positron emitter impurities; (iv) Calibration of the CENTRONIC IG12/20A ionization chamber; (v) Calibration of commercial radionuclide calibrators.