| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1879369 | Applied Radiation and Isotopes | 2010 | 4 Pages |
Abstract
Catalysis for reaction of electrophilic fluorine addition to a fluorinated double bond is described. The presence of small amounts of iodine, bromine, or boron trifluoride increases an overall product yield and degree of fluorine incorporation, making the reaction a more efficient method for preparation of 18F positron emission tomography agents. A possible mechanism of catalytic action of iodine is discussed.
Keywords
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Alexander V. Kachur, William R. Dolbier Jr., Wei Xu, Cameron J. Koch,