Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1879371 | Applied Radiation and Isotopes | 2010 | 6 Pages |
Abstract
A convenient remote controlled synthesis of a new tryptophan analog, l-5-(2-[18F] fluoroethoxy)-tryptophan (5-18FEHTP) was described. The radiochemical yield within 65 min was about 12–16% without decay correction, the radiochemical purity was over 98%, and 5-18FEHTP dissolved in saline was stable over 6 h at room temperature. The biodistribution of 5-18FEHTP in mice and the high uptake of 5-18FEHTP in tumor demonstrated that it is very likely a new PET tracer for tumor imaging.
Keywords
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Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Ruifen Li, Shih-Chen Wu, Shih-Chen Wang, Zhe Fu, Yonghong Dang, Li Huo,