The methoxylation of N-formylpyrrolidine in a microfluidic electrolysis cell for routine synthesis

A single channel microfluidic electrolysis cell being developed for application alongside other routine microfluidic operations in the laboratory has been applied to the methoxylation of N-formylpyrrolidine. It is shown that very high conversions (≫90%) in a single pass can be achieved and it is possible to obtain several grams of product per hour with a good selectivity in optimised conditions.