Rate acceleration of Diels–Alder reactions utilizing a fluorous micellar system in water

A fluorous micellar system in water has been created to produce a large interfacial area between these media that retains substrates, effectively facilitating intermolecular Diels–Alder reactions due to repulsion effects from both media. Because LiFOS functioned not only as a surfactant but also as a supporting electrolyte, an electrochemical approach could be introduced to evaluate the rate acceleration effects. The measurement of the particle size distribution of the fluorous micelles clearly supported these evaluations.

► We create a fluorous micellar system in water to produce a large interfacial area. ► The fluorous micelles retain substrates to facilitate intermolecular Diels-Alder reactions. ► We introduce an electrochemical approach to evaluate the effect of the micelles.