Article ID Journal Published Year Pages File Type
1902347 Ageing Research Reviews 2013 10 Pages PDF
Abstract
► Primary cultures of HPMCs display extremely short replicative lifespan in vitro. ► Young HPMCs are highly vulnerable to exogenous oxidative stress. ► Senescent HPMCs accumulate in the peritoneum in vivo. ► There is a correlation between donor age and replicative HPMC lifespan. ► Senescent HPMCs promote the intraperitoneal spread of cancer cells.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Authors
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