Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1904482 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2016 | 10 Pages |
Abstract
Hypertension in Plin1Â â/â mice might occur as a deleterious consequence of PVAT dysfunction. This finding provides the direct evidence that links dysfunctional PVAT to vascular dysfunction and hypertension, particularly in pathophysiological states. This hypertensive mouse model might mimic and explain the hypertension occurring in patients with adipose tissue dysfunction, particularly with Plin1 mutations.
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Authors
Liangqiang Zou, Weiyi Wang, Shangxin Liu, Xiaojing Zhao, Ying Lyv, Congkuo Du, Xueying Su, Bin Geng, Guoheng Xu,