| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1905199 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2011 | 10 Pages |
Abstract
⺠Vasogenic edema of the ischemic brain was reduced in female mice compared males. ⺠AQP4 levels in the ischemic cortex were maintained in female mice. ⺠Down-regulated AQP4 levels by ovariectomy were reversed by estrogen replacement. ⺠An ERs antagonist reduced AQP4 levels with an increase of vasogenic edema. ⺠Estrogen receptors may regulate AQP4 levels to prevent the ischemic brain edema.
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Authors
Jin A. Shin, Ji Ha Choi, Youn-Hee Choi, Eun-Mi Park,