Enhanced targeting of mitochondrial peroxide defense by the combined use of thiosemicarbazones and inhibitors of thioredoxin reductase

Article ID	Journal	Published Year	Pages	File Type
1907784	Free Radical Biology and Medicine	2016	12 Pages	PDF

Keywords

DMEM TrxR1 PRX1 TRX2 TrxR2 Dp44mT PRXs Prx3 CDDP ANF PMSF HBSS SeCys Cys GPX N-ethylmaleimide FBS DMSO l-NAME ROS Trx1 Auranofin Iron Triapine thioredoxin reductase Thioredoxin-2 Thiosemicarbazones Thioredoxin-1 Dimethylsulfoxide fetal bovine serum Selenocysteine cisplatin Cysteine phenylmethylsulfonyl fluoride Hank’s balanced salt solution Dulbecco’s modified eagle’s medium NEM Peroxiredoxin-3 Peroxiredoxins glutathione peroxidase Reactive oxygen species

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Ageing

Enhanced targeting of mitochondrial peroxide defense by the combined use of thiosemicarbazones and inhibitors of thioredoxin reductase

Authors

Charles R. Myers,