Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1908847 | Free Radical Biology and Medicine | 2012 | 7 Pages |
Abstract
⺠Glycochenodeoxycholate (GCDC) induced alveolar epithelial (AECII) death in vitro. ⺠Oxidative stress and mitochondrial damage were detected in GCDC-treated AECII. ⺠Reactive oxygen species (ROS) scavengers and caspase inhibitors rescued cell death. ⺠Rat AECII surfactant secretion was inhibited by glycochenodeoxycholate.
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Authors
Hu Zhangxue, Gao Min, Zhao Jinning, Shi Yuan, Wang li, Song Huapei, Li Rui, Zeng Chunyu,