Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1916027 | Journal of the Neurological Sciences | 2007 | 10 Pages |
Abstract
This article highlights the experimental and clinical data, controversies and postulated mechanisms surrounding osmotherapy with hypertonic saline (HS) solutions in the neurocritical care arena and builds on previous reviews on the subject. Special attention is focused on HS therapy on commonly encountered clinical paradigms of acute brain injury including traumatic brain injury (TBI), post-operative “retraction edema”, intracranial hemorrhage (ICH), tumor-associated cerebral edema, and ischemia associated with ischemic stroke.
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Authors
Wendy C. Ziai, Thomas J.K. Toung, Anish Bhardwaj,