Article ID Journal Published Year Pages File Type
1916261 Journal of the Neurological Sciences 2007 6 Pages PDF
Abstract

Modern medicine is facing an increasing number of treatments available for vascular and neurodegenerative brain diseases, but no causal or neuroprotective treatment has yet been established. Almost all neurological conditions are characterized by progressive neuronal disfunction, which, regardless of the pathogenetic mechanism, finally leads to neuronal death. Many agents that proved neuroprotective in experimental studies failed in achieving this goal within clinical studies. This paper briefly reviews the latest etiopathogenetic theories regarding nervous system disorders and the most important endeavors in neuroprotection.

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Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
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