Article ID Journal Published Year Pages File Type
1918038 Maturitas 2011 8 Pages PDF
Abstract

ObjectiveMany postmenopausal women use herbal remedies and dietary supplements to counteract menopausal symptoms, including the decline in cognitive function. The aim of this systematic review is to evaluate the evidence regarding the efficacy of herbal and dietary supplements on cognition in menopause.DesignRandomized clinical trials (RCTs) of herbal medicines and dietary supplements were identified using the Medline, EMBASE, AMED, PsycINFO, CINAHL and The Cochrane Library 2010 (Issue 2) electronic databases and by hand searches. Data were independently extracted and evaluated by two reviewers. Risk of bias was assessed by two independent reviewers using the Cochrane Collaboration tool.ResultsTwelve RCTs were included and five of these suggest that isoflavone, soy and Gingko biloba supplementation may improve cognition in postmenopausal women. However, most of the included studies had serious methodological flaws which demand a cautious interpretation of these findings.ConclusionsThe evidence that herbal and dietary supplements might positively affect the cognitive decline during the menopause is not compelling.

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Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
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