Article ID Journal Published Year Pages File Type
1919369 Mechanisms of Ageing and Development 2011 10 Pages PDF
Abstract
▶ Podospora anserina genome encodes for a bona fide PARP. ▶ Overexpression of PARP in P. anserina leads to phenotypical deficiencies. ▶ PaParp overexpression leads to mitochondrial impairments. ▶ PaParp overexpressors display increased sensitivity to stressors. ▶ PaParp overexpressors are characterized by an increased sensitivity towards apoptosis.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
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Overexpression of PaParp encoding the poly(ADP-ribose) polymerase of Podospora anserina affects organismal aging
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