Article ID Journal Published Year Pages File Type
1919414 Mechanisms of Ageing and Development 2010 8 Pages PDF
Abstract
▶Myocardium regulates coronary vascular tone by metabolites. ▶ Aging increases the production of superoxide in myocardium.▶ Aging decreases catalase and SOD activities in myocardium. ▶ Aging increases the production of H2O2 and angiotensin via the redox pathway. ▶ H2O2 and angiotensin regulate age-related decline of coronary vasodilation.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Preview
Aging impairs myocardium-induced dilation in coronary arterioles: Role of hydrogen peroxide and angiotensin
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