Article ID Journal Published Year Pages File Type
1919727 Mechanisms of Ageing and Development 2010 12 Pages PDF
Abstract
▶ WRN deficiency results in hyperrecombinogenic mitotic homologous recombination. ▶ WRN may cooperate mechanistically with ERCC1-XPF in resolving intermediates. ▶ WRN is important for efficient nonhomologous recombination.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Preview
Depletion of Werner helicase results in mitotic hyperrecombination and pleiotropic homologous and nonhomologous recombination phenotypes
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