Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1921673 | Parkinsonism & Related Disorders | 2006 | 6 Pages |
Abstract
To assess cerebral hemodynamics in patients with multiple system atrophy (MSA), cerebral blood flow and oxygenation were evaluated in 7 MSA patients and 9 healthy controls during a head-up tilt test (HUT) by means of transcranial Doppler ultrasonography and near-infrared spectrophotometry. In the MSA patients examined, the perfusion pressure reduction during HUT was marked, but severe reduction in blood flow velocity was prevented because of a decrease in cerebrovascular resistance. The MSA patients showed no severe reduction in cerebral oxygenation during HUT. These findings indicate that our MSA patients exhibited a compensatory cerebral vasodilatation response to orthostatic hypotension.
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Authors
Masato Asahina, Jiro Sato, Masatoshi Tachibana, Takamichi Hattori,