Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1921796 | Parkinsonism & Related Disorders | 2006 | 6 Pages |
Abstract
We assessed the efficacy of chronic stimulation of the subthalamic nucleus (STN-DBS) in 20 patients with Parkinson's disease (PD) by means of clinical assessments and patient diaries 12 months after surgery.STN-DBS reduced the UPDRS part III off-medication score by 33%, and successively improved complete daily on-time without dyskinesia at 12 months significantly.In conclusion, our study demonstrates the efficacy of chronic STN-DBS on motor features in a selected population of advanced PD patients. In addition to clinical assessments, patients' diaries serve as an essential tool to evaluate the functional motor status after STN-DBS.
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Authors
A.T. Portman, T.van Laar, M.J. Staal, A.W.F. Rutgers, H.L. Journee, K.L. Leenders,