| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1922590 | Parkinsonism & Related Disorders | 2007 | 5 Pages |
Abstract
The pedunculopontine nucleus (PPN) is a brainstem locomotive center that also processes sensory and behavioral information. Through its connections with basal ganglia structures and the spinal cord, the PPN may play a role in axial motor symptoms in Parkinson's disease (PD). We review the anatomical features of the PPN, its role in motor control, and its potential role as a target for PD surgery, including the results of recently published clinical studies.
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Authors
Clement Hamani, Scellig Stone, Adrian Laxton, Andres M. Lozano,