Uncoupling protein-2 attenuates palmitoleate protection against the cytotoxic production of mitochondrial reactive oxygen species in INS-1E insulinoma cells

Article ID	Journal	Published Year	Pages	File Type
1923078	Redox Biology	2015	9 Pages	PDF

Keywords

DAPI Krebs–Ringer–HEPES buffer MitoSOX GSIS NEFA KRH UCP2 Tris-buffered saline with Tween-20 TBST DPBS PBS HEPES SDS FBS 4′,6-diamidino-2-phenylindole 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid BSA ROS bovine serum albumin EDTA Ethylenediaminetetraacetic acid Mitochondrial dysfunction Non-esterified fatty acid non-esterified fatty acids Glucose-stimulated insulin secretion Cytoprotection Type 2 diabetes sodium dodecyl sulphate fetal bovine serum Pancreatic beta cells Glucolipotoxicity Uncoupling Protein-2 Phosphate-buffered saline Obesity Hydroethidine DHE Reactive oxygen species

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Ageing

Uncoupling protein-2 attenuates palmitoleate protection against the cytotoxic production of mitochondrial reactive oxygen species in INS-1E insulinoma cells

Authors

Jonathan Barlow, Verena Hirschberg Jensen, Charles Affourtit,