Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
192524 | Electrochimica Acta | 2008 | 8 Pages |
Abstract
An improved procedure has been developed using a catalytic amount of a nickel(II) complex in the efficient and selective electrochemical cyclization of propargyloxy and allyloxy bromo derivatives into substituted tetrahydrofurans using ethanol and ethanol–water mixtures as environmental-friendly systems. The reduction of the substrates proceeded via one-electron cleavage of the carbon–bromine bond to form a radical-type intermediate that undergoes cyclization to afford the tetrahydrofuran structures in good yields.
Graphical abstractNi(II)-catalyzed radical-type cyclization of unsaturated bromoethers to the corresponding cyclic compounds in EtOH and EtOH–H2O mixtures. Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Chemical Engineering (General)
Authors
E. Duñach, M.J. Medeiros,