Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
200631 | Fluid Phase Equilibria | 2016 | 8 Pages |
Abstract
•Binary systems based on modified Boltorn H and a surfactant for doxorubicin encapsulation.•The effect of Boltorn H functionalization degree on doxorubicin encapsulation degree.•The effect of polymer/surfactant concentration ratio on doxorubicin encapsulation degree.
Doxorubicin fixation by hyperbranched polyester polyol Boltorn H acid derivatives and their binary systems in the presence of a surfactant (Brij-35, Triton X-100) was investigated. Doxorubicin fixation degree nonlinearly depends on the number of acid groups in the polyester polyacid. Polyacid/surfactant binary systems fix up to 60% of doxorubicin from the solution.
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Physical Sciences and Engineering
Chemical Engineering
Chemical Engineering (General)
Authors
Artur A. Khannanov, Marianna P. Kutyreva, Nikolay A. Ulakhovich, Alfiya R. Gataulina, Olga V. Bondar, Lucia Ya. Zakharova, Gennadiy A. Kutyrev,