| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2034378 | Biologicals | 2011 | 8 Pages |
Abstract
This review covers comprehensive data accumulated during the long history of using monkeys in the determination of neurovirulence activity and safety of live poliomyelitis, flaviviral, smallpox and mumps vaccines, as well as newly developed transgenic mouse and molecular-biological tests. The review also analyzes processes caused by some of these viruses in infant rodents (mice, rats) and evaluates the role of these processes in vaccine safety control. Recommendations resulting from this analysis are presented.
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Authors
Inessa Levenbook,