| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2035024 | Cell | 2016 | 4 Pages |
Abstract
Nonsense-mediated mRNA decay (NMD) is a eukaryotic mRNA quality control and regulatory process that plays direct roles in human health and disease. In this Minireview, we discuss how understanding the molecular events that trigger NMD can facilitate strategic targeting of genes via CRISPR/Cas9 technologies and also inform disease diagnostics and treatments.
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Authors
Maximilian W. Popp, Lynne E. Maquat,