Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2035942 | Cell | 2012 | 9 Pages |
Abstract
⺠Smokers with lung cancer show 10à the number of point mutations than never-smokers ⺠Novel lung cancer genes, including DACH1, CFTR, RELN, ABCB5, and HGF were identified ⺠Novel pathway alterations in lung cancer include cell-cycle and JAK-STAT pathways ⺠Alterations were identified in 54 genes for which targeted drugs are available
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Authors
Ramaswamy Govindan, Li Ding, Malachi Griffith, Janakiraman Subramanian, Nathan D. Dees, Krishna L. Kanchi, Christopher A. Maher, Robert Fulton, Lucinda Fulton, John Wallis, Ken Chen, Jason Walker, Sandra McDonald, Ron Bose, David Ornitz,