| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2036694 | Cell | 2010 | 13 Pages |
Abstract
⺠TRIOBP, an actin-associated protein, localizes to hair cell stereocilia rootlets ⺠Purified TRIOBP protein organizes F-actin into uniquely dense rootlet-like bundles ⺠Stereocilia in TRIOBP-deficient mice lack rootlets and degenerate, causing deafness ⺠Mechanosensory stereocilia lacking rootlets are hyperflexible and fragile
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Authors
Shin-ichiro Kitajiri, Takeshi Sakamoto, Inna A. Belyantseva, Richard J. Goodyear, Ruben Stepanyan, Ikuko Fujiwara, Jonathan E. Bird, Saima Riazuddin, Sheikh Riazuddin, Zubair M. Ahmed, Jenny E. Hinshaw, James Sellers, James R. Bartles, John A. III,