Article ID Journal Published Year Pages File Type
2036702 Cell 2010 13 Pages PDF
Abstract
► ErbB ligands EGF and HRG induce transient versus sustained cytoplasmic ERK activity ► Nuclear ERK activity and c-fos mRNA expression are transient for both ligands ► HRG induces increased expression of c-fos, ERK phosphatases, and a c-fos repressor ► Signaling-transcription cascades robustly discriminate different ERK dynamics
Related Topics
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Authors
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