| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2037518 | Cell | 2008 | 6 Pages |
Abstract
Recent studies of calorie restriction in several organisms demonstrate an increase in mitochondrial activity that is associated with the salutary effects of this dietary restriction regimen. In this Essay, I speculate on how an increase in mitochondrial activity might provide benefit and discuss how diet, mitochondria, and sirtuins might interact in a pathway to slow aging and associated diseases.
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Authors
Leonard Guarente,