| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2037952 | Cell | 2007 | 4 Pages |
Abstract
The “immortal strand” hypothesis proposes that asymmetrically dividing stem cells selectively retain chromosomes containing “old” DNA to prevent accumulation of mutations. As I describe in this Essay, such a possibility seems unlikely. An alternative explanation is that asymmetric cell divisions and cell fate are codirected by epigenetic differences between sister chromatids.
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Authors
Peter M. Lansdorp,