Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2038427 | Cell | 2006 | 4 Pages |
Abstract
Transcriptional activators need to be modulated and eventually switched off after the initial event that triggers their activation. Here, we discuss how ubiquitination of activators and their proteasome-mediated turnover are crucial steps in this process.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry, Genetics and Molecular Biology (General)
Authors
Thomas Kodadek, Devanjan Sikder, Kip Nalley,