Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2038791 | Cell | 2006 | 4 Pages |
Abstract
Exosomes and proteasomes are macromolecular complexes that posttranscriptionally regulate gene expression by degrading mRNAs and proteins, respectively. Although the two complexes act on different substrates and are composed of different subunits, they share a similar barrel-like architecture that appears to have evolved to restrict substrate access and prevent indiscriminate degradation.
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Authors
Esben Lorentzen, Elena Conti,