Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2040875 | CMGH Cellular and Molecular Gastroenterology and Hepatology | 2016 | 23 Pages |
Abstract
Proximal colonic DC subsets differ from those in distal colon and are more mature. Targeted immunotherapy using DC in T-cell mediated GI tract inflammation may therefore need to reflect this immune compartmentalization.
Keywords
ILT3CCLCCR2MDCTregSPBCFSEHuman gastrointestinal tractPDCFITCCCRPBMCAMOVASIRPαFACSLPMCMϕregulatory T-cellsinterleukinsodium phosphate bufferanalysis of molecular varianceDetection limitfluorescence-activated cell sortingGastrointestinalRaldh2Plasmacytoid dendritic cellLamina Propria Mononuclear Cellsperipheral blood mononuclear cellsDendritic cellsMyeloid dendritic cellfluorescein isothiocyanatechemokine (C-C motif) ligandMacrophagesMicrobiotapolymerase chain reactionPCRSignal regulatory protein αDistal colonProximal colon
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Authors
David Bernardo, Lydia Durant, Elizabeth R. Mann, Elizabeth Bassity, Enrique Montalvillo, Ripple Man, Rakesh Vora, Durga Reddi, Fahri Bayiroglu, Luis Fernández-Salazar, Nick R. English, Simon T.C. Peake, Jon Landy, Gui H. Lee, George Malietzis,