| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2040951 | CMGH Cellular and Molecular Gastroenterology and Hepatology | 2015 | 11 Pages |
Abstract
Oxidized LDL is a novel predictor of SVR after interferon-based therapy and may explain the previously observed association of LDL with SVR. Rather than being a marker of activated antiviral defenses it may improve chances of SVR by limiting spread of infection to naive cells through the cell-to-cell route.
Keywords
PBSRFPoxLDLpegylated interferon αHCVccSR-BIRBVPEG-IFNNLSDAADMEMSVRDTTROCDulbecco’s modified Eagle mediumdithiothreitolRibavirinnuclear localization signalOxidized low-density lipoproteinLow-density lipoproteinLDLPhosphate-buffered salineHepatitis C virusHCVhydrochlorideSustained virologic responsered fluorescent proteinCell-to-cell spreadreceiver operating characteristic
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry, Genetics and Molecular Biology (General)
Authors
Philipp Solbach, Sandra Westhaus, Maximilian Deest, Eva Herrmann, Thomas Berg, Michael P. Manns, Sandra Ciesek, Christoph Sarrazin, Thomas von Hahn,