| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2041163 | CMGH Cellular and Molecular Gastroenterology and Hepatology | 2015 | 22 Pages |
Abstract
IL33 is highly expressed in the gastric mucosa and promotes the activation of T helper 2-cytokine-expressing cells. The loss of IL33 expression after prolonged H pylori infection may be permissive for the T helper 1-biased immune response observed during H pylori infection and subsequent precancerous progression.
Keywords
qRT-PCRSS1IL33T-helperILCHBSSNF-κBERKmRNAFBSSMCSPFmessenger RNATffalcian blueSTATperiodic acid–SchiffinterleukinEnzyme-linked immunosorbent assayELISAGastric cancerfetal bovine serumDendritic cellinnate lymphoid celltrefoil factornuclear factor-κBSignal transducer and activator of transcriptionHank’s balanced salt solutionPASwild typeHelicobacter pyloriInflammatory responsepolymerase chain reactionquantitative reverse-transcription polymerase chain reactionPCRspecific pathogen freeExtracellular signal–regulated kinase
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Authors
Jon N. Buzzelli, Heather V. Chalinor, Daniel I. Pavlic, Philip Sutton, Trevelyan R. Menheniott, Andrew S. Giraud, Louise M. Judd,