Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2054401 | International Journal of Medical Microbiology | 2006 | 7 Pages |
Abstract
Pheromone-inducible transfer of the plasmid pCF10 in Enterococcus faecalis is regulated using a complicated network of proteins and RNAs. The plasmid itself has been assembled from parts garnered from a variety of sources, and many aspects of the system resemble a biological kluge. Recently several new functions of various pCF10 gene products that participate in regulation of plasmid transfer have been identified. The results indicate that selective pressures controlling the evolution of the plasmid have produced a highly complex regulatory network with multiple biological functions that may serve well as a model for the evolution of biological complexity.
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Authors
Briana K. Kozlowicz, Martin Dworkin, Gary M. Dunny,