Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2065230 | Toxicon | 2008 | 8 Pages |
Abstract
Anatoxin-a (ANTX) and homoanatoxin-a (HANTX) are low molecular weight neurotoxic secondary amines of 165 and 179 Da, respectively. We applied matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF-MS) for the detection of ANTX and HANTX directly on lyophilized and fresh filaments of axenic strains of the genus Oscillatoria, using 2,5-dihydroxybenzoic acid as matrix and purified ANTX and HANTX as references. To counteract the span of low molecular mass ions (
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Authors
Rómulo Aráoz, Vincent Guérineau, Rosmarie Rippka, Nicolae Palibroda, Michael Herdman, Olivier Laprevote, Hans von Döhren, Nicole Tandeau de Marsac, Marcel Erhard,